GLP-1 receptor agonistslike semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and their peershave transformed how we treat type 2 diabetes and obesity
Patients underwent neurocognitive assessments (lexical access, memory impairment, memory recall), motor evaluations, and anthropometric and metabolic measurements
Retatrutide may require particular caution or may not be suitable for individuals with: A personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) based on findings in rodent studies, this is a precaution shared across the GLP-1 receptor agonist class in EU and UK product information
TGF transduction is involved in the degradation of the perineural network around inhibitory neurons and reactive excitatory synapse formation, promoting the recurrence of seizures and pathological neural excitation (158, 159)