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It works by mimicking a natural hormone in the body that helps regulate blood sugar levels and appetite
It enhances fat metabolism by increasing lipoprotein lipase activity in white adipose tissue
The mixed model repeated measures analysis, a restricted-maximum-likelihood-based model, was used to analyze continuous longitudinal variables
Postulated renoprotective effects include constriction of afferent glomerular arterioles (via SGLT2i-mediated diuresis, natriuresis, and reduction of natriuretic peptides) leading to suppression of tubuloglomerular feedback along with reduction in renin and angiotensin II production, leading overall to efferent arterioles dilatation and a reduction in glomerular hydrostatic pressure
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