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Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

It is important to emphasize that tirzepatide-specific research in addiction remains limited compared to other GLP-1 receptor agonists like semaglutide and exenatide, which have more published data in this area

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