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Objective markers (IGF-1, metabolic panels, and where tested, biological age) typically show measurable improvement
However, clinical studies of the drug have focused on surgical patients
Megaloblastic anemia Diminished activity of methionine synthase in vitamin B 12 deficiency inhibits the regeneration of tetrahydrofolate (THF) and traps folate in a form that is not usable by the body ( Figure 3 ), resulting in symptoms of folate deficiency even in the presence of adequate folate
W., Massie, A., Smolders, I., Methner, A., Pergande, M., Smith, S
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