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Small molecule inhibitors as tools to scan for active pathways do not conclusively rule out the participation of a signaling mediator if a negative result is obtained (i.e., no inhibition/augmentation of a toxic endpoint)
The revealed capacity of DSIP to increase the efficiency of oxidative phosphorylation found in vitro experiments could contribute to understanding pronounced stress protective and antioxidant action of this peptide in vivo
That said, its worth noting that the evidence supporting these uses is still limited, and more research is needed
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