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Multiple experiments indicate that GCL is the rate-limiting enzyme in the plant glutathione biosynthesis (Foyer et al., 1995, 1997
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Sheehan D, Meade G, Foley V, Dowd C (2001) Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily
converting liquid volume into the selected syringe scale.
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