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And, although relatively rare, some people can develop pancreatitis, or inflammation of the pancreas
The SURMOUNT-1 trial (N=2,539) reported a vomiting rate of 12.2% for tirzepatide 15 mg, lower than the 24.8% seen with semaglutide 2.4 mg in STEP 1, although cross-trial comparisons have significant limitations [16]
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The hypothalamic glucagon-like peptide 1 receptor Is sufficient but not necessary for the regulation of energy balance and glucose homeostasis in mice
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