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The final study population included 174,678 individuals with T1D, contributing 6,092,537 person-trials across the 135 trials (Extended Data Fig

The 2020-2025 Dietary Guidelines for Americans suggests that limiting calories to 1,200 per day is too low for most people to meet their nutritional needs, plus its unsustainable for long-term health and well-being

Wegovy and Zepbound also have a more convenient dosing regimen as once-weekly injections, compared with Saxenda, which requires a daily injection

For guidance on preserving muscle during GLP-1 treatment, the article on strength training on Ozempic is a practical starting point