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Low glutathione levels can result from poor production, inefficient recycling, and increased need

Dihexa or its analogs were administered 5 minutes after scopolamine, either intracerebroventricularly at doses of 0.1 or 1 nmol), intraperitoneally at doses of 0.05, 0.25, or 0.50 mg/kg, or orally at doses of 1.25 or 2.0 mg/kg

In vitro studies have shown that the ferroptosis inducer erastin can inhibit the proliferation of granulosa cells and promote their ferroptosis (Pan et al., 2024)

Future research should focus on optimizing carrier materials, enhancing tissue targeting selectivity, and ensuring long-term biosafety to advance their clinical application prospects in antioxidant therapy for RIRI