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Similarly, exposure to heavy metals such as lead, cadmium, and mercury can disrupt redox balance by catalyzing the production of ROS through Fenton-like reactions or by depleting cellular antioxidants [40]
de Meester C (1984)
West MB, Hill BG, Xuan YT, Bhatnagar A
Furthermore, MPTP-treated mice exhibited significantly upregulated expression levels of iNOS, TNF, and IL-1 compared to controls, whereas irisin treatment notably attenuated the expression of these pro-inflammatory markers (Fig
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