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The presence of benign thyroid nodules does not require dose modifications, delayed initiation, or special monitoring beyond what is already recommended for the nodules themselves

Smith G, Ng MT, Shepherd L, Herrington CS, Gourley C, Ferguson MJ, Wolf CR (2012) Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer

Most fertility and metabolic specialists recommend stopping GLP-1 medications at least 2-3 months before attempting to conceive

At higher doses, tirzepatides side effects can be more pronounced, which makes sense, since the dose ceiling is higher and you need those higher doses to achieve the stronger results