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doi: 10.1038/s41467-024-46314-8 32 MaithaniR.TulsawaniR

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This concentration works well for those wanting to dose in 100mcg increments, such as 300mcg (0.15ml) or 400mcg (0.2ml)

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A later study showed MOTS-c is also exercise-induced: levels rise sharply in muscle and blood during physical activity, and treated older mice nearly doubled their running capacity (Reynolds et al., 2021, Nature Communications)

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Users pursuing more aggressive body recomposition may use 200-400mg weekly, though this requires more careful monitoring

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