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(PubMed) Fulgoni VL, 3rd, Keast DR, Bailey RL, Dwyer J
Sources: the REDEFINE 1 program (obesity, n3417) and REDEFINE 2 (type 2 diabetes, n1206) for the cagrilintide + semaglutide combination (NEJM 2025)
They mimic the hormone amylin, which works alongside insulin to regulate appetite and slow gastric emptying
Risks: Combination Protocol Analysis Building on safety data and protocol design considerations, its time to weigh the benefits and risks of combining tesamorelin with CJC-1295/ipamorelin
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