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A role of the enzyme in modulating stress responses by controlling JNK activity was also proposed 56, 57

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Unlike other growth factors, which need carrier(s) addition, and are rapidly destroyed in human gastric juice, BPC 157 is native and stable in human gastric juice for more than 24 h (Sikiric et al., 2018

Strategies to mitigate lean muscle loss while on treatment include optimising dietary protein, recognising that GLP-1 and GIP/GLP-1 receptor agonists may suppress appetite and substantially reduce overall energy intake, increasing the risk of inadequate protein consumption.260-262 Regular resistance exercise training can help preserve lean muscle mass during weight loss and should be performed on two or more days per week, where clinically appropriate.159 Dietary advice for people on incretin-based medications Incretin-based medications increase the risk of muscle loss, sarcopenic obesity and nutrient deficiencies