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Joseph Rizzo, senior author of the July 2024 study that found an association between semaglutide and NAION, called the condition, in effect, a stroke of the optic nerve. Rizzo is the director of neuro-ophthalmology at Mass Eye and Ear in Boston

Further evidence will be necessary before we can see the complete picture, but they show promise as, at the minimum, an adjunct to current therapy, says Esposito

Improved Insulin Sensitivity: Helps cells respond better to insulin, making the hormone more effective at lowering blood sugar

Serious side effects Although less common, Zepbound can also cause more serious side effects that may require immediate medical attention