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coli , oxidants promote S-glutathionylation of the MarR repressor (a MarR-family protein), reducing its DNA binding and derepressing the mar operon (including acrAB )

Possible Short-Term Side Effects Some people may experience the following short-term side effects: Headache Nausea Abdominal discomfort Mild allergic reactions Skin rash or itching Side Effects Related to Glutathione Injections When glutathione is given through the IV or IM route, additional risks may occur, such as: Pain or irritation at the site of injection Allergic reactions (the most severe side effect) Infection (if injections are not done under proper sterile conditions) Potential Long-Term Concerns If someone uses glutathione for long-term or in high doses, then there are chances for more significant side effects, such as: Kidneys problems Thyroid problems Bronchospasm (inhaled glutathione can trigger it) Kidney and thyroid-related effects have been reported in some cases, but a direct causal relationship remains unclear due to limited evidence

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The aim is to separate promising ideas from treatments that have been properly tested in humans, especially when Crohns disease or ulcerative colitis may be active