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If improved even slightly, that is a positive sign suggesting adaptation is occurring

Participants also showed improvements in cardiovascular risk factors, including waist circumference, non-HDL cholesterol, triglycerides, systolic blood pressure, and high-sensitivity C-reactive protein (hsCRP)

1 Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is currently one of the most important public health issues in the world because it is directly related to metabolic disorders such as obesity, insulin resistance, and type 2 diabetes mellitus (T2DM) ( MASLD is particularly notorious for being able to accelerate the development of T2DM, a chronic metabolic disease characterized by hyperglycemia, IR, and beta cell failure ( The main pathophysiological mechanisms through which Insulin resistance (IR), hepatic lipid accumulation, and low-grade inflammation lead to MASLD and T2DM have been described ( 2 Epidemiological data With the prevention and control of many infectious diseases, Non-Communicable Diseases (NCDs) have become the leading global diseases burden (32)

It is a biological process that may contribute to inflammation and tissue injury when the balance between oxidants and antioxidants remains disrupted