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This targeted delivery method provides immediate availability of this crucial nutrient needed for energy production, neurological function, red blood cell formation, and DNA synthesis

Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

The question: does sustained elevation of intracellular NAD+ via NNMT inhibition produce the same long-term benefits as NAD+ precursor supplementation (like nicotinamide riboside or NMN), or are there trade-offs we haven't identified yet