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Psychiatrists and other mental health professionals sound the alarm that taking GLP-1s may provoke not only distress associated with uncomfortable side effects, but unhealthy eating habits

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For instance, a 2017 review of two studies showed that taking L-carnitine for 3 days had no effect on markers of brain function including reaction time, vigilance, immediate memory, and delayed recall in young adults without cognitive impairment

Another consideration: NNMT is highly expressed in adipose tissue and liver but also present in the brain, kidneys, and vascular endothelium