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All of three dual agonist peptides, tirzepatide, MAR709 and CY-5, have a C-terminal same as exenatide but no convincing reasons have been put forward and its use is more likely an inertia from MAR709
Behavioural strategies can help manage the psychological aspects of discontinuation
Never discontinue semaglutide without medical guidance, particularly if using it for diabetes management, as abrupt cessation may affect glycemic control
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