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Ships within 48 hours · Estimated delivery Sep 27 - Oct 2
We take FCF as ~100% of net income in normal years
The GLP-1 biosimilars market is gaining significant momentum, driven by the global surge in obesity and type 2 diabetes prevalence, escalating healthcare costs, and the growing need for accessible treatment options
Key takeaways Oral Wegovy (semaglutide 25 mg) is currently the only UK-licensed oral GLP-1 option for weight loss in the UK
IRS recruitment activates phosphoinositide 3-kinase (PI3K), which phosphorylates PIP2 to PIP3, recruiting Akt/PKB to the membrane for activation by PDK1 this PI3K/Akt arm drives protein synthesis via mTORC1, glucose uptake via GLUT4 translocation, and cell survival via BAD phosphorylation
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