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If you find that your appetite is significantly reduced or that certain foods do not appeal to you during the adjustment phase, having weekend flexibility allows you to eat smaller portions, choose blander options, or simply wait until you feel ready to eat without the constraints of lunch breaks or workplace social eating situations

doi: 10.1016/j.ejphar.2019.172844 78 HitomiHKiyomotoHNishiyamaA

[3] Adverse Events: The most common adverse events associated with Mounjaro are gastrointestinal in nature, including nausea, vomiting, diarrhea, decreased appetite, and abdominal pain

These lipodystrophic changes result from the medications effect on local fat tissue