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Another triple agonist candidate, Hanmis efocipegtrutide (HM15211), is in a phase 1 trial for weight loss and in a phase 1b/2a for nonalcoholic fatty liver disease (NAFLD)
Data from open-label and placebo-controlled trials with over 4000 adults with obesity or DM2 demonstrate that once-weekly injections of tirzepatide at doses of 515mg result in substantially more weight loss compared to placebo or semaglutide after 4072 weeks of treatment
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