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Some studies have reported that depression caused by chronic stress disrupts the BDNFtropomyosin related kinase B (TrkB) receptor signaling pathway in the PFC and hippocampus, and ultimately contributes to impaired synaptic maturation, synaptic protein synthesis, and glutamate receptor cycling (Duric et al., 2010
Less than six months after starting the medication, Winfrey stopped on her 70th birthday in January 2024
Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study
Tricyclic antidepressants (TCAs) Amitriptyline and nortriptyline: Effective in managing PDPN by inhibiting monoamine reuptake and blocking sodium channels
