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These results can provide insight into whether a B12 deficiency exists

Revisiting Vitamin B12 Deficiency: A Clinicians Guide For the 21st Century Low Plasma Vitamin B12 Is Associated With Lower BMD: The Framingham Osteoporosis Study Clinical manifestations and diagnosis of vitamin B12 and folate deficiency Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency (Review) Mentioned in This Article: Vitamin B12 Vitamin B12 is essential for red blood cell formation and DNA production

This suggests that during in vitro reprogramming there is also a high demand of B 12 and Met, which we explored further using pharmacological manipulation of the Met cycle