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It acts as a non-selective melanocortin receptor agonist with the following binding profile (approximate Ki values): MC1R : ~0.67 nM (highest affinity, melanogenesis) MC4R : ~6.6 nM (appetite suppression, sexual function) MC3R : ~34 nM (energy balance) MC5R : ~46 nM (exocrine gland function) This broad receptor profile produces multiple physiological effects
Why Bioavailability is the Key to Support When we realize our antioxidant levels might be lower than ideal, the first instinct is often to reach for a supplement
Douros, A
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