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The relief from migraines lasted for the full three-month observation period, the researcher noted, although weight loss was "modest and statistically non-significant." Participants weight stayed about the same during the trial, suggesting that the headache reductions werent tied to weight loss

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Further docking studies with aldose reductase, DPP-4, PPAR, and glucosidase revealed that chalcones 13, 16, 17, 18, and 19 (Figure 4) inhibited DPP-4 activity more effectively than others