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Whether youre prescribed a brand-name version or compounded semaglutide , your starting point is almost always the same: a low-dose introduction phase
Since many people on GLP-1 medications also manage cholesterol with statins, the double depletion can produce significant fatigue and muscle weakness
This difference can change how it acts inside the body
More serious but less common adverse effects include: Pancreatitis : Patients should seek immediate medical attention if experiencing severe, persistent abdominal pain radiating to the back Gallbladder disease : Rapid weight loss can increase the risk of gallstones Hypoglycaemia : Particularly when used alongside other diabetes medications such as sulphonylureas or insulin Diabetic retinopathy complications : Rapid improvement in blood glucose control may temporarily worsen retinopathy in susceptible individuals Acute kidney injury : Usually in the context of dehydration from vomiting or diarrhoea Animal studies have shown an increased incidence of thyroid C-cell tumours with semaglutide, though the human relevance of this finding is unknown
