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doi: 10.3389/fnagi.2025.1495769 Received 13 September 2024 Accepted 28 March 2025 Published 09 May 2025 Volume 17 - 2025 Edited by Ramesh Kandimalla, Indian Institute of Chemical Technology (CSIR), India Reviewed by Chunchen Xiang, Capital Medical University, China Bruno piljak, University of Zagreb, Croatia Updates Copyright 2025 Li, Zhang, Yu, Xue and Hu
A review published in PubMed found that berberine induces GLP-1 secretion in the intestine by altering the bacterial profile and promoting short-chain fatty acid production from intestinal L-cells
For example, if free cortisol is high, but metabolised cortisol is low, this is indicative of possible slow thyroid function and therefore slow overall metabolism, which may be contributing to your weight gain
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