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Your health history: Your doctor will consider your overall health, including any pre-existing conditions like heart disease, kidney disease, or a history of pancreatitis

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VESPER-1 VESPER-1 was a 28-week randomized, double-blind, placebo-controlled trial that assessed the efficacy and safety of once-weekly berobenatide across a range of dose levels (0.4 to 1.2 mg) in adults with obesity or overweight with hypertension and/or dyslipidemia

This insulin-stimulating effect could be inhibited by different agents such as diltiazem, yohimbine, propranolol, or a combination of atropine, propranolol, and yohimbine