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Animal studies have reported various effects, including potential lifespan extension in rodent models and improvements in certain biomarkers associated with aging

Wegovy and Zepbound's pivotal trials saw discontinuations due to AEs range from 2.6% to 7.1% depending on the dose

The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis

As Drucker points out, 'The strange thing is that you can't find many GLP-1 receptors in all these other organs where GLP-1 seems to work' (Lunenfeld-Tanenbaum Research Institute)