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The review describes anti-inflammatory, antipruritic, and anti-aging properties for topical THC based on mechanistic and preclinical evidence, but it is not a clinical trial proving efficacy for any specific diagnosis.What kind of study is this?It is a peer-reviewed narrative review published in the International Journal of Molecular Sciences that synthesizes cutaneous biology findings across cannabinoids, antidepressants, and psychedelics.What did the review say specifically about THC and skin?The authors describe topical THC as showing anti-inflammatory, antipruritic, and anti-aging properties in the literature they reviewed, with therapeutic potential they say deserves further study.Is this the same as a systematic review or meta-analysis?No

Ann N Y Acad Sci 2004;1033:158-67