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Key findings from the SURMOUNT-OSA trial The SURMOUNT-OSA trial evaluated tirzepatide versus placebo in adults with moderate-to-severe OSA (AHI 15) and obesity, including both CPAP users and non-users
It is important to distinguish between oral supplementation and other forms, such as intravenous (IV) injections
Age influences outcomes through multiple mechanisms
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Overall, when administering GLP-1RA plus SGLT2i combination therapy, it is important to adopt an individualized approach to therapy taking into account individual preferences, costs and coverage, AE profile, consideration of kidney function and glucose-lowering efficacy, desire for weight loss, and comorbidities such as frailty [6, 22, 24]
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