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In the study, alcohol-dependent rats were treated with semaglutide, which significantly reduced their alcohol consumption and even reduced the drinking of alcohol in conjunction with relapses

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Patients on tirzepatide were twice as likely to lose at least 25% of their body weight, and nearly one in five (19.7%) lost 30% or more, compared to fewer than one in fourteen (6.9%) on semaglutide.[1] Both medications also improved blood pressure, blood sugar, and cholesterol levels, with greater improvements seen in the tirzepatide group, which tracked with the larger weight reduction.[1] The safety profiles were similar