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Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2
Tirzepatide works, but stopping it reverses the gains
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide a chain of 15 amino acids that is a fragment of a natural protective protein (BPC), discovered in gastric juice
These experimental compounds work through various proposed mechanisms, such as stimulating melanocortin receptors in the brain, but lack robust clinical evidence and carry significant safety concerns
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