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The body has to do something else with those signals, and for many this can lead to an increase in anxiety, depression or other negative emotions
One explanation for this appears to be a negative-feedback inhibition of L-cell secretion by the elevated levels of active GLP-1 brought about by DPP-IV inhibition (47), an effect which may be mediated by a paracrine action of somatostatin secreted from neighboring D-cells in the gut (97, 98)
GLP-1 receptor agonists: A new treatment in parkinsons disease
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