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A role for mineralocorticoid receptor antagonism in DKD has been appealing with a strong physiological rationale, since mineralocorticoid receptors are widely expressed in kidney and cardiac tissue, and their activation by aldosterone leads to hemodynamic and non-hemodynamic effects culminating in inflammation, fibrosis, and progression of cardiac and kidney disease [9097]

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Common GLP-1 medications include: GLP-1 medications are FDA-approved for: Health regulators have also approved some GLP-1 medications to help people living with type 2 diabetes, obesity, or overweight reduce associated risks, including cardiovascular risk and the progression of chronic kidney disease