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Oral Ozempic Delivers Mixed Results on Alcohol Use Semaglutide in pill form shows promise for alcohol use disorder STUDY: Schacht JP et al, American Journal of Psychiatry 2026 STUDY TYPE: Randomized, double-blind, placebo-controlled trial FUNDING: National Institute on Alcohol Abuse and Alcoholism, National Center for Advancing Translational Sciences, Hewit Family Foundation, anonymous donor Background GLP-1 drugs like semaglutide (Ozempic) have a mix of positive and negative data in alcohol use disorder, but most of the research has involved non-treatment seeking populations, which often differ in their responses

If delaying treatment poses a greater health risk, a clinician may initiate a GLP-1 while continuing to work on thyroid stabilization in parallel

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