In the United States, there is a boxed warning of the possible risk, and those with personal or family histories of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 are therefore advised to avoid liraglutide, dulaglutide, exenatide extended release, and semaglutide
Patients with reduced receptor sensitivity may tolerate slower dose escalation better, potentially experiencing less severe constipation
Yes, it is essential to discuss your Crohn's disease activity, nutritional status, gastrointestinal complications, and treatment goals with your GP, gastroenterologist, and diabetes specialist before starting GLP-1 therapy to ensure a coordinated, safe approach
However, for those who take an SGLT2 inhibitor and have frequent or bothersome yeast infections, consulting with a healthcare provider about different treatment options, such as metformin, may be a good idea