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Several drugs, including colchicine, have been reported to reduce the absorption of methylcobalamin, vitamin B12
Different reconstitution volumes produce different concentrations from the same vial: 50mg vial + 2ml water = 25mg/ml (very concentrated) 50mg vial + 2.5ml water = 20mg/ml (concentrated) 50mg vial + 5ml water = 10mg/ml (standard) 50mg vial + 10ml water = 5mg/ml (dilute) Higher concentrations require smaller injection volumes but may exceed solubility limits for some peptides
If you have been on long term medication like omeprazole or lansoprazole, have had a poor diet or are vegan/vegetarian you may benefit from having a course of Vitamin B12 Injections
Its worth noting that vitamin B12 shots arent appropriate for everyone
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