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5%EGCG cream is the optimal concentration for the treatment of vitiligo (Zhu et al., 2014)

Mechanism of action, pharmacokinetics, clinical efficacy and adverse effects

4.12 Iodine Iodine concentration is primarily regulated by the thyroid through the synthesis of T4 and T3 hormones, which are stored in follicular colloid (the body's main iodine reserve) and whose release is stimulated by TSH via a negative feedback mechanism

But several factors work against this natural recovery process, including age (collagen production drops roughly 1% per year after age 20), the amount of weight lost (more than 50 pounds creates significantly more laxity), how long the excess weight was carried, sun damage history, smoking, genetics, and the speed at which the weight came off