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These can be signs that the kidneys need extra attention

The goal is to send the signal that muscle is needed so the body preferentially burns fat rather than lean tissue during the weight loss process

Abstract Bimagrumab is an investigational antibody targeting type II activin receptors, intended to reduce total body and visceral fat mass and promote muscle growth

The ASTRAAS trial (NCT04714320) evaluated changes in SBP from baseline to day 85 as the primary endpoint, whereas the ASTRAAS-HF trial (NCT04836182) investigated whether IONIS-AGT-LRx could serve as an adjunct therapy to standard treatment in patients with HFrEF