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In addition, there was upregulation in the expression of the proinflammatory cytokine Tnf and genes involved in the integrated stress response ( Atf3 , Atf5 , Ddit3 and Dele1 ) and reduced expression of the adipokine Adipoq
WHY SHOTSY
Developed as type 2 diabetes treatments, glucagon-like peptide-1 (GLP-1) receptor agonists mimic the effects of GLP-1, a hormone produced naturally by the body to regulate hunger and blood sugar
Results Patient characteristics All 15 participants were female, and randomly assigned to receive either exenatide (n = 7) or placebo (n = 8)
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