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Based on our data, we propose that T3 has a regulatory role in insulin-controlled glucose metabolism, and T3 exerts this function by increasing non-12-OH FXR-antagonistic BA levels via downregulating the expression of CYP8B1, which potentiates GLP-1 production via suppressing the intestinal FXR signaling

Monte has had patients who have consumed the recommended dosage and still suffered negative side effects

Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1c targets

When patients know what to expect and how to handle side effects, they can take better care of themselves and avoid serious problems