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Phase 2b ACCESS Study of Aleniglipron in Adults with Obesity or Overweight , published in Press release (Structure Therapeutics) (Structure Therapeutics investigators, 2025): ACCESS II Exploratory Study of Higher-Dose Aleniglipron , published in Press release (Structure Therapeutics) (Structure Therapeutics investigators, 2025): We summarize new studies, safety updates, and dosing insights delivered biweekly

When studies reported multiple GLP-1RAs, we prespecified the inclusion of Semaglutide to ensure comparability across studies and minimize heterogeneity

Cryo-EM structures of peptide activated GLP-1R published from 2017 onwards (see Zhang et al and Liang et al) provided the first high-resolution view of class B GPCR activation

PMID 8405712