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Die Anwendung erfolgt kontrolliert, transparent und immer im Rahmen medizinischer Verantwortung

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doi: 10.1186/s13046-019-1210-3 277 NiemanKMKennyHAPenickaCVLadanyiABuell-GutbrodRZillhardtMRet al

In one study, chronic treatment with a low dose of clozapine (0.5 mg/kg) increased the number of bromodeoxyuridine (BrdU)-positive cells in the dentate gyrus 24 hours after BrdU administration, whereas haloperidol (0.05 or 2 mg/kg) or a high dose of clozapine (20 mg/kg) had no significant effect.134 Interestingly, the increased BrdU-positive cells with a low dose of clozapine could not survive or integrate into existing hippocampal circuitry