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Philp, D., et al
Monotreme GLP-1 elicits a different signalling cascade compared to hGLP-1 when binding to the GLP-1 receptor Closer examination of potencies in receptor activation revealed differential signalling bias for monotreme GLP-1 peptides in comparison to that elicited by hGLP-1
Stress triggers the release of cortisol, a hormone that can lead to increased cravings for high-calorie foods and may contribute to fat accumulation, particularly in the abdominal area
Moderate weight loss of 5 to 10% ameliorates cardiovascular risk factors such as hyperglycemia, hypertension, and dyslipidemia
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