The standard titration schedule for Wegovy, for example, involves four-week dose increases over approximately 16 weeks before reaching the full maintenance dose
Whats more, its demographic analysis showed significant differences between the GLP-1 RA and comparator groups in factors such as age, HbA1c, body weight, BMI, duration of diabetes, sex, race, and so on, suggesting that the effect of GLP-1RAs on DR is yet controversial and that it may vary based on the specific GLP-1RA used, as well as the patients demographic and clinical characteristics
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Across the SURPASS trials for type 2 diabetes, nausea affected 12% to 24% of participants depending on the dose