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Key characteristics of NAION include: Sudden vision loss, often upon waking Permanent damage with no proven treatment to restore vision Increased risk of vision loss in the other eye Significant impact on quality of life, independence, and ability to work For many patients, the NAION-related optic nerve damage is life-altering and irreversible

These findings underscore the need to monitor who is accessing these medications and to ensure their safe, appropriate, and equitable provision

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Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency