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Many people live for years with low vitamin B12 levels without realizing it, mistaking the symptoms for stress, aging, or poor sleep

This review will expound on the application of engineered bacteria based on synthetic biology in the medical field and highlight ECB, especially the huge application prospect of ECB in the disease field and some challenges of ECB construction, revealing the great potential of ECB in the future medical field and hoping to provide theory and data support for extensive application of ECB in the future healthcare field

However, they are not a one-size-fits-all solution